Engineered materials that integrate advances in polymer chemistry, nanotechnology, and biological sciences have the potential to create powerful medical therapies. My research is at the forefront and interface of cellular biology, microtechnology, and the science of biomaterials. The overarching goal of my research is to formulate and foster practical solutions that restore or enhance the health of individuals. Specifically, my lab is interested in developing advanced fibrous materials for tissue engineering and drug delivery. Fibers are 1D flexible materials and can be formed into literally any shape using well-established textile methods or 3D printing. Fiber-shape tissues with high anisotropic mechanical and chemical properties similar to those observed in native tissues can be engineered by 3D printing, electrospinning, and textile methods (e.g., embroidering, weaving, braiding, etc.). Further, fibers with diameters ranging from tens to hundreds of micrometers can be embroidered into tissues with minimum damage to the tissue for measuring biological markers or releasing drugs directly to the disease site. In this talk, I will present my group’s recent efforts in producing advanced multifunctional fibers for use in tissue engineering and drug delivery. This talk will encompass our work on bioink development, methods for producing meter-long multifunctional hydrogel fibers with controllable biophysical and biochemical features, techniques used to assemble functional fibers and create highly complex fibrous constructs, and in vitro and in vivo models we use to evaluate the safety and performance of engineered fibrous materials for clinical translation.